Figure 2. Clinical significance of TMEM25 in ccRCC. The differential expression of TMEM25 was analyzed in different clinical states such as OS (A), DSS (B), PFI (C), T stage (D), N stage (E), M stage (F), pathologic stage (G) and histologic grade (H). (I) The ROC curve demonstrated a strong ability of TMEM25 in distinguishing ccRCC patients from normal patients (AUC value of 0.903). The prognosis of ccRCC patients in the TMEM25 high expression group was significantly better than that of the low expression group in terms of OS (J), DSS (K), and PFI (L). (***p < 0.001).