Figure 2. Analysis of gene regulation by Mn2+ in macrophages. (A) Heat map of cellular gene regulation after Mn2+ treatment. (B) Volcano plot of differentially expressed genes with a log-fold change (logarithmic value of differential gene expression) cut-off value of 1.966. (C) Histogram of GO enrichment terms. (D) Chord plot of enriched genes and their related pathways. (E) GO terms of upregulated and downregulated genes. (F) Heatmap of enrichment results.