← Back
Research Paper Volume 15, Issue 23 pp 13608—13627

Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction

class="figure-viewer-img"

Figure 1. AGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maximum relaxation by Ach (10−4 M) in aorta from Figure 1B. Results are expressed as percent relaxation ± SEM. (n = 4; #p < 0.05 vs. control). Abbreviations: Phe: phenylephrine; NCD: normal chow diet; HFD: high fat diet; AGE: Angelica gigas NAKAI extract.