Figure 5.Multiple aggrephagy cell subtypes influenced the prognosis and immunotherapy response of LUAD patients. (A) The landscape of all cell-cell communication within all identified aggrephagy subtypes. (B) A hazard ration of different aggrephagy subtypes in 8 LUAD cohorts. (C) Odd ratio produced by logistic regression of different subtypes in 8 cohorts. (D–L) All aggrephagy cell subtypes could distinguish the survival of patients in Meta cohort. (M) Various aggrephagy-related subtypes demonstrated significantly different infiltration in responders and non-responders of ICB in TCGA cohorts, as predicted by TIDE. Mann Whitney-Wilcoxon test was applied between responders and non-responders. *p < 0.05; **p < 0.01; ***p < 0.001. Abbreviation: ns: not significant.
