Research Paper Volume 15, Issue 23 pp 14242—14262
Two lncRNA signatures with cuproptosis as a novel prognostic model and clinicopathological value for endometrioid endometrial adenocarcinoma
Figure 8. Cuprotosis cell model and expression of ACOXL-AS1, mir-421 and MTF1 in endometrial cancer cells. (A) Colony formation ability under differential conditions as determined by a colony formation assay. (B) Proliferation of endometrial cancer cells is detected by the Cell Counting Kit-8 assay. (C, D) Relative expression of ACOXL-AS1, mir-421 and MTF1 in endometrial cancer cells under different conditions. (E) overexpress the ACOXL-AS1 gene in HEC-1A and HHUA cells, while the “negative control lentiviral vector” is used as a reference (F) The impact of ACOXL-AS1 overexpression on the expression levels of MTF1 and miR-421, **p < 0.01, ***p < 0.001, ****p < 0.0001.