Research Paper Volume 15, Issue 23 pp 14172—14191

Gypenoside IX restores Akt/GSK-3β pathway and alleviates Alzheimer’s disease-like neuropathology and cognitive deficits

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Figure 8. GP reactivates AKT/GSK-3β pathway in STP rats. (A) Western blots for AKT/GSK-3β pathway-related proteins. (BD) Quantification of the relative protein levels (p-AKT (308), p-AKT (473), s9-GSK-3β) after normalization to the β-actin signal. Data represent mean ± SEM, p-value significance is calculated from one-way ANOVA, n = 3. *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001.