Research Paper Volume 15, Issue 23 pp 13920—13943

Figure 3. GADD45B regulated cell cycle in melanoma. (A) The associated molecular network of GADD45B in melanoma. Different colored arrows represent different types of action. The legend is listed on the right. (B) The enrichment analysis of GADD45B associated network. (C–F) Flow cytometry was used to detect the proportion of A375 in each stage of cell cycle. Different absorption peaks represent different stages of cell cycle, and the area under each absorption peak curve represents the proportion of cells in this period. The proportion of cells in each period was listed on the right side of the peak diagram after statistics, showing the proportion of cells in G1, S and G2 phases respectively. At the same time, the proportion of cells in each group at different stages was statistically analyzed by corresponding histograms. Blue represents G1 phase, green represents S phase, and red represents G2 phase. * p-value < 0.05, ** p-value < 0.01, *** p-value < 0.001.