Figure 3 — HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2

Research Paper|Volume 15, Issue 23|pp. 13888–13900

HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2

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Figure 3.The inhibition of HACE1 promoted oxidative stress in vitro model. HACE1 mRNA expression (A), MDA, ROS, SOD, GSH and GSH-px levels (B–F), collagen I, collagen III and TGF-β mRNA expression (G–I). ##p<0.01 compared with si-nc group. Immunofluorescence images of si-HACE1 activity (J).