Research Paper Volume 15, Issue 22 pp 13239—13264

Figure 2. A visualization network construction and target-organ localization network for the treatment of Alzheimer’s disease (AD) with Qi Fu Yin (QFY) established by network pharmacology. (A) The targets related to AD among those predicted by QFY were selected. Purple represents Alzheimer’s disease targets, yellow represents QFY-predicted targets, and pink represents targets related to AD among those predicted by QFY. (B) Compound-Target-Disease (C-T-D) network: compound-target-AD network in which the purple nodes represent compounds, the pink nodes represent targets, and the lines between the nodes represent the interactions between compounds and targets. (C) Target-organ localization network. The screened target genes were used to establish a network with 84 human organs, including the heart (66 targets, red), liver (65 targets, yellow), kidney (10 targets, purple), and brain (34 targets, blue). The details refer to Supplementary Material 3: Supplementary Table 3.