Research Paper Volume 15, Issue 22 pp 13194—13212

Electroacupuncture ameliorates AOM/DSS-induced mice colorectal cancer by inhibiting inflammation and promoting autophagy via the SIRT1/miR-215/Atg14 axis

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Figure 1. EA and RSV ameliorated the AOM/DSS-induced CRC in mice. (A) Experimental procedures. (B) Representative macroscopic images of colon tumor and colon measurements. (C) Colon length in each group. (D) Number of tumors in each group. (E) Changes in bodyweight and (F) DAI score. The notation "(W)" stands for "weeks”. (G) Representative HE staining of colorectal tissues (100× magnification). Data are expressed as mean ± SD (n = 8). ###p < 0.001, compared to the control group; *p < 0.05, **p < 0.01, and ***p < 0.001, compared to the model group.