Research Paper Volume 15, Issue 22 pp 12749—12762

Nectandrin B significantly increases the lifespan of Drosophila - Nectandrin B for longevity

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Figure 2. NecB improved the locomotion activity of D. melanogaster. (A) Oregon-RC males, (B) Oregon-RC females, (C) DGRP-100 males and (D) DGRP-100 females. Ctrl represents standard cornmeal medium; Rap-50 represents cornmeal medium supplemented with Rapamycin at 50 μg/mL; Rap-200 represents cornmeal medium supplemented with Rapamycin at 200 μg/mL; NecB-50 represents cornmeal medium supplemented with NecB at 50 μg/mL; and NecB-200 represents cornmeal medium supplemented with NecB at 200 μg/mL (Supplementary Table 1). The locomotor activity was observed on the 30th, 60th, and 90th day and indicated as performance index. The data are from three independent experiments, and values are shown as mean ± s.e.m. An unpaired Student’s t-test was used for the statistical analysis; n = 15, *p < 0.05, **p < 0.01, ***p < 0.001.