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Research Paper Volume 15, Issue 23 pp 13669—13679

Atorvastatin mitigates memory deficits and brain monocyte infiltration in chronic hypercholesterolemia

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Figure 2. Treatment with Atorvastatin alleviated memory impairment in aged ApoE-/- mice. (A) Recognition index (RI) in the long-term memory test; (B) Recognition index (RI) in the spatial short-term memory test; (C) The mobility (%) was measured in the open field test. (D) The mRNA level of PSD-95 and BDNF in the hippocampus tissue was checked by RT-PCR (*, P<0.05 vs. vehicle; #, P<0.05 vs. ApoE-/- mice group).