Research Paper Volume 15, Issue 22 pp 12890—12906
TJP3 promotes T cell immunity escape and chemoresistance in breast cancer: a comprehensive analysis of anoikis-based prognosis prediction and drug sensitivity stratification
Figure 9. TJP3 regulates GEM-induced cell apoptosis and EMT process. (A) Immune Score predicted by SangerBox (http://vip.sangerbox.com/login.html). (B) T cell infiltration predicted by SangerBox (http://vip.sangerbox.com/login.html). (C) Immune cell infiltration predicted by TIMER2.0 (http://timer.comp-genomics.org/timer/). (D) Anti-PD1 prognosis in TJP3 low and high expression groups. (E) Anti-PD1 response differences between TJP3 low and high expression groups. (F) Si-RNA down-regulates TJP3 expression, and the corresponding down-stream targets expression features. (G) Statistical analysis, normalized by GAPDH. (H) Recombinant plasmid up-regulation TJP3 expression, and the corresponding down-stream targets expression features. (I) Statistical analysis, normalized by GAPDH. *p < 0.05, **p < 0.01, ***p < 0.001.