Research Paper Volume 15, Issue 23 pp 13655—13668

Down-regulation of EZH2 genes targeting RUNX3 affects proliferation, invasion, and metastasis of human colon cancer cells by Wnt/β-catenin signaling pathway

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Figure 1. Effect of transfection in colon cancer cells HCT116, HT29 on the expressions of EZH2, RUNX3, CEA, CA199, MMP-9, VEGF, β-catenin and CyclinD1 genes. (A) Relative expression of EZH2, RUNX3, CEA, CA199, MMP-9, VEGF, β-catenin and CyclinD1 genes in HCT116 cells; (B) Relative expression of EZH2, RUNX3, CEA, CA199, MMP-9, VEGF, β-catenin and CyclinD1 genes in HT29 cells. (**P < 0.01; N=3/Group).