Research Paper Volume 15, Issue 21 pp 12369—12387

Figure 4. Suppressed CCL19 expression exerts progressive phenotype and apoptosis activity of BRCA and OV. (A) IHC analysis of BRCA and OV samples showed that the expression of CCL19 in normal tissues was higher than that in tumor tissues. (B) Analysis by software package RESM showed that the expression level of CCL19 in normal tissues is lower than that in tumor tissues in breast cancer samples. (C) The difference of CCL19 expression in different subtypes of breast cancer was analyzed. (D) The expression of CCL19 in four clinical stages was observed and compared, and the expression of CCL19 in stage 4 patients was the lowest. (E) Apoptosis activity was tested in CCL19^high group and CCL19^low group in BRCA and OV. With higher expression of CCL19, the apoptosis activity is higher.