Research Paper Volume 15, Issue 21 pp 12314—12329

Figure 4. Function, pathway and GSEA analyses of DLAT-related genes. (A) Co-expression cycle graph of the 13 genes closely related to DLAT. The red line represents a positive correlation, while the green line represents a negative correlation. (B) GO circle graph of co-expressed genes. First circle: The top 9 GO terms, with the coordinate scale showing the gene number outside the circle. Second circle: The number of GO terms and Q values in the background gene. Third circle: Number of GO term associated genes. Fourth Circle: Abundance factor values for each GO term associated gene. (C) Bubble map of co-expressed genes from KEGG. (D) Function enrichment analysis between high- and low-expression groups of DLAT by GSEA. (E) Pathways analysis between high- and low-expression groups of DLAT by GSEA. (F) Pathways for valine, leucine and isoleucine degradation. Red represents key genes with high expression, while green represents key genes with low expression. BP: biological process; CC: cell component; MF: molecular function; GSEA: Gene Set Enrichment Analysis.