Research Paper Volume 15, Issue 21 pp 12171—12191

CENPB promotes the proliferation of hepatocellular carcinoma and is directly regulated by miR-29a

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Figure 3. CENPB protein levels were found to be associated with the prognosis of patients within early-stage subgroups. (A, B) High CENPB protein expression predicted a shorter OS (A) and RFS (B) time for patients in stage I/II. (C, D) High CENPB protein expression predicted a shorter OS (C) and RFS (D) time for patients with AFP <400ng/ml. (E, F) High CENPB protein expression predicted a shorter OS (E) and RFS (F) time for patients with tumor size smaller than 5cm. (G, H) High CENPB protein expression predicted a shorter OS (G) and RFS (H) time for without cirrhosis patients. (I, J) High CENPB protein expression predicted a shorter OS (I) and RFS (J) time for patients with free of vascular invasion. (K, L) High CENPB protein expression predicted a shorter OS (K) and RFS (L) time for patients with median/well differentiation.