Research Paper Volume 15, Issue 21 pp 12021—12067
Utility of G protein-coupled oestrogen receptor 1 as a biomarker for pan-cancer diagnosis, prognosis and immune infiltration: a comprehensive bioinformatics analysis
Figure 2. The expression of GPER1 mRNA in pan-cancer. (A) Pan-cancer expression of GPER1 between tumor and normal tissues in unpaired sample analysis; (B) Pan-cancer expression of GPER1 between tumor and paracancerous tissue in unpaired sample analysis; Based on publicly available data, molecular distinctions across diverse pan-cancer datasets are directly analyzed to perform comparative analysis between the tumor group and the normal (adjacent) group. (C) Paired sample analysis of GPER1 between tumor and normal tissues in BLCA, BRCA, CHOL, COAD, ESCA, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, PAAD, PRAD, READ, STAD, THCA and UCEC. Each line represents a paired sample, namely the normal (adjacent) versus tumor samples selected from the available public data. The more consistent and inclined the trend direction of the lines, the more pronounced the differences between the two groups. Wilcoxon rank sum test * p < 0:05, ** p < 0:01, *** p < 0:001.