Research Paper Volume 15, Issue 21 pp 11875—11890

MicroRNA-30a-3p: a potential noncoding RNA target for the treatment of arteriosclerosis obliterans

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Figure 6. MicroRNA-30a-3p inhibited neointima formation. (A) LV-miR-30a-3p increased microRNA-30a-3p levels in the balloon injury model (qRT-PCR, n=6). (B, C) Neointima formation was inhibited by LV-miR-30a-3p (n=12). LV-miR-30a-3p suppressed VSMC proliferation as shown by the Ki67 analysis (D) (WB, n=4) and (E, F) (IF, n=6). Scale, 50 μm (bottom of B, E), 200 μm (top of B); **=0.005, ***=0.001.