Research Paper Volume 15, Issue 20 pp 11532—11545

Indoxyl sulfate induced frailty in patients with end-stage renal disease by disrupting the PGC-1α–FNDC5 axis

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Figure 2. Pathologic change in skeletal muscle in mice with 5/6 nephrectomy. (A) Experimental design. (B) H&E staining of skeletal muscle tissues. (C) Number of nuclei within the skeletal muscle for each group. *p < 0.05.