Research Paper Volume 15, Issue 20 pp 11331—11368

Exosome and lipid metabolism-related genes in pancreatic adenocarcinoma: a prognosis analysis

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Figure 2. Model establishment for prognosis. (A) Venn diagram: the blue circle on the left includes the 576 ERGs, the red circle on the right includes the 695 LMRGs, and the intersection of the two circles includes the 52 EALMRGs. (B) Forest plot to show the result of univariate Cox regression analysis. (C) The confidence interval under each lambda. (D) The changing trajectory of each independent variable. (E) Risk score nomogram consists of 3 parts, including risk group, survival outcomes, and heatmap. (FH) The calibration curves of the nomogram are at 1-year (F), 3-year (G), and 5-year (H), respectively. The X-axis in curves represented nomogram predicted survival probability and Y-axis represented observed fraction survival probability. (IK) DCA diagrams of the models for 1-year (I), 3-year (J), and 5-year (K), respectively. The X-axis in DCA diagrams represents Threshold Probability and the Y-axis represents Net Benefit. LASSO, Least absolute shrinkage and selection operator; TCGA, The cancer genome atlas; OS, Overall survival; DCA, decision curve analysis; LASSO, least absolute shrinkage and selection operator.