Research Paper Volume 15, Issue 20 pp 11313—11330

Role of NF-κB pathway in kidney renal clear cell carcinoma and its potential therapeutic implications

class="figure-viewer-img"

Figure 3. (A) All KIRC samples were divided into medium-, high-, and low-expression groups (clusters 1, 2, and 3), according to the level of NF-κB expression, and dark red and blue represent an increase and decrease in mRNA expression, respectively. The redder or bluer the color, the closer the NF-κB score is to 0.4 or -0.4, respectively. Cluster analysis is divided into three groups: red, green, and black for clusters 1, 2, and 3, respectively. (B) Enrichment and scores of the three clusters. (C) Survival curves for three cluster analyses. (D) Clinical pathological features of three clusters of KIRC patients. *: p<0.05, **: p<0.01, ***: p<0.001.