Research Paper Volume 15, Issue 20 pp 11298—11312

Single-cell landscape and spatial transcriptomic analysis reveals macrophage infiltration and glycolytic metabolism in kidney renal clear cell carcinoma

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Figure 5. The use of single-cell RNA sequencing analysis has allowed for the identification of immune cell populations. (A, B) The relative proportions of each cell type found within the two datasets, while showcasing the proportion of integrated immune cells present within the databases. UMAP is an abbreviation for the Unified Manifold Approximation and Projection technique used in this study. Visual representations of all KIRC cells from both GEO datasets are depicted in (C, D) through the utilization of Unified Manifold Approximation and Projection (UMAP) and assigned specific colors according to clusters.