CDKN2A was a cuproptosis-related gene in regulating chemotherapy resistance by the MAGE-A family in breast cancer: based on artificial intelligence (AI)-constructed pan-cancer risk model

Hong Wan; Xiaowei Yang; Guopeng Sang; Zhifan Ruan; Zichen Ling; Mingzhao Zhang; Chang Liu; Xiangyang Hu; Tao Guo; Juntong He; Defeng Liu; Jing Pei

doi:doi:10.18632/aging.205125

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Research Paper Volume 15, Issue 20 pp 11244—11267

CDKN2A was a cuproptosis-related gene in regulating chemotherapy resistance by the MAGE-A family in breast cancer: based on artificial intelligence (AI)-constructed pan-cancer risk model

Figure 4. CRCGs-based multi-gene risk-score. TCGA data are used to construct a multi-gene risk-score model, and C-index is higher than 0.7 in ACC (HR=1.254[1.121-1.], P=8.25e-05), KICH (HR=1.117[1.060-1.178], P=3.78e-05), KIRP (HR=1.172[1.101-1.248], P=6.73e-07), THCA (HR=1.066[1.037-1.095], P=4.58e-06), and UVM (HR=1.157[1.096-1.222], P=1.30e-07).