Research Paper Volume 15, Issue 20 pp 11152—11161

The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway

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Figure 4. The inactivation of AMPK/ACC signaling pathway in T2DM rats was promoted by DA3-CH. (A) The protein levels of p-AMPK and p-ACC were measured with western blotting; (B) The protein expression was analyzed; (C) The mRNA levels of AMPK and ACC were detected with RT-PCR. * means p <0.05. n=3 for each group.