Research Paper Volume 15, Issue 19 pp 10640—10680
Multi-omics analysis of MRPL-13 as a tumor-promoting marker from pan-cancer to lung adenocarcinoma
Figure 13. Effect of MRPL13 down-regulation on the proliferation, cell cycle, apoptosis of LUAD. (A) MRPL13 knockdown validation in A549 and NCI-H1975. (B, C) CCK8 and Colony formation detection of the effect of down-regulation of MRPL13 expression on the proliferation of LUAD cells. (D) The percentage of apoptosis in control group and MRPL13 down-regulated group was analyzed by flow cytometry. (E) The effect of low expression of MRPL13 on cell cycle distribution was detected by flow cytometry. *p-value < 0.05, **p-value < 0.01, ***p-value < 0.001, and ****p-value < 0.0001.