Figure 10. The role of PITX3. (A) Differential expression of PITX3 in normal and tumor samples of TCGA. (B) Survival differences in high and low PITX3-expressing samples. (C) Differential genes between samples with high and low expression of PITX3, results are presented in volcano plots. (D) Pathways of differential gene enrichment in GO. (E, F) GSEA enrichment analysis in the high- and low-PITX3 expressing groups.