Research Paper Volume 15, Issue 19 pp 10237—10252

Ginkgolide attenuates memory impairment and neuroinflammation by suppressing the NLRP3/caspase-1 pathway in Alzheimer’s disease

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Figure 8. Effects of ginkgolide on the mRNA expression levels of (A) ASC, (B) NLRP3, and (C) caspase-1 in the brains (hippocampus and cerebral cortex) of APP/PS1 transgenic mice. Abbreviations: ASC: apoptosis-associated speck-like protein containing a CARD; APP/PS1: amyloid precursor protein/presenilin 1; NLRP3: nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3; WT: wild-type.