Research Paper Volume 15, Issue 19 pp 10213—10236

Figure 6. ICT inhibited the mitochondrial membrane potential and reduced mitochondrial fusion and fission. (A) Representative fluorescence photographs of mitochondrial membrane potential stained by JC-1. (B) Quantitative analysis of membrane potential by measuring the ratio of red and green fluorescence intensity. (C) Representative protein bands of Parkin, DRP1, FIS1, and MFN2. (D) Quantitative analysis of Parkin, DRP1, FIS1, and MFN2. All data were presented as mean ± SD, n = 3, ^*P < 0.05; ^**P < 0.01; ^***P < 0.001; ^****P < 0.0001.