Research Paper Volume 15, Issue 17 pp 9167—9181

Figure 5. Role of Jing Shi and Jing Shi-preconditioned human adipose-derived stem cells (hADSCs) on cardiac function in doxorubicin-challenged Sprague–Dawley rats. (A) M-mode echocardiography results showing contractility functions (i.e., left ventricular internal diameter end diastole and end systole. (LVIDd and LVIDs)) of all rat groups, indicated by the blue arrow. Doxorubicin-challenged Sprague–Dawley rats treated with Jing Shi-preconditioned human adipose-derived stem cells (hADSCs) showed similar patterns to that of the control group. (B, C) The ejection fraction (EF%) and fractional shortening (FS%) of control, doxorubicin, and various treatment groups. Jing Shi-preconditioned hADSCs showed an improved repair of heart function in Doxorubicin-challenged Sprague–Dawley rats. Experiments were performed in triplicate. Data are presented as means are represented as means ± SEM. *p <0.05, **p <0.01, and ***p <0.001 were significant.