Research Paper Volume 15, Issue 17 pp 9105—9127
Gut microbiota and hypertensive disorders in pregnancy: evidence from the Mendelian randomization study
Figure 5. Schematic representation of the MR analysis. The three assumptions of MR are as follows: (1) Instrumental variables must be associated with gut microbiota, (2) Instrumental variables must not be associated with confounders; and (3) Instrumental variables must influence hypertensive disorders in pregnancy only through gut microbiota, not through other pathways.