Research Paper Volume 15, Issue 17 pp 9041—9058
Galectin-3 promotes brain injury by modulating the phenotype of microglia via binding TLR-4 after intracerebral hemorrhage
Figure 6. Downregulation of Gal-3 can improve ethology deficits after ICH. (A) Representative track of Morris water maze experiment during 29-34 days after ICH. (B) Representative track of Morris water maze experiment on 35 days after ICH. (C) Foot fault test. (D, E) Latency distance and time of Morris water maze experiment during 29-34 days after ICH. (F, G) Time in target quadrant and frequency cross the platform of Morris water maze experiment on 35 days after ICH. (H) Neurobehavioral score. Higher scores suggest less neurobehavioral deficits. (I) The motor coordination ability of rats after ICH was evaluated by rotarod test, long latency time indicates good motor coordination ability. (J) Adhesive-removal test. The black dots represent individual data in each group. **p < 0.01 and *p < 0.05 vs. Sham group, @p < 0.05 vs. ICH+shRNA-con group, &&p < 0.01 and &p < 0.05 vs. ICH+Lv-con group, n = 18.