Research Paper Volume 15, Issue 17 pp 8993—9021
Identification and validation of a prognostic signature of cuproptosis-related genes for esophageal squamous cell carcinoma
Figure 4. GSVA and construction of cuproptosis score prognosis signature. (A, B) GSVA enrichment analysis between two consensus clusters in TCGA-ESCC dataset, involved group comparison chart (A) and ComplexHeatmap (B). (C) The heat map indicated a correlation among the expression level of 12 CRGs from TCGA-ESCC dataset. (D, E) Correlation scatter plot showed the correlation between two pairs of CRGs, included DLAT and FDX1 (D), GLS and PDHB (E). (F) Differential analysis of Cuproptosis score among two ESCC subtypes. (G) Kaplan–Meier OS curves for patients in the high-and low- score group.