Research Paper Volume 15, Issue 17 pp 8908—8929
TIMP1 shapes an immunosuppressive microenvironment by regulating anoikis to promote the progression of clear cell renal cell carcinoma
Figure 5. The immune infiltration characteristics of Anoikis index. (A) Distribution of immune cells in high and low AI groups under multiple algorithms; (B) The correlation between immune cells and AI under multiple algorithms; (C–E) The differential expression of immunosuppressive cells between high and low AI groups (C) Macrophage; (D) MDSC; (E) Regulatory.T.cell; (F–H) The differential expression of tumor microenvironment scores between high and low AI groups (F) ImmuneScore; (G) StromalScore; (H) ESTIMATEScore; (I) The differential expression of immune checkpoints between high and low AI groups. The asterisks represented the statistical p-value (*p<0.05, **p<0.01, ***p<0.001).