Research Paper Volume 15, Issue 17 pp 8812—8832

SUMO1-regulated DBC1 promotes p53-dependent stress-induced apoptosis of lens epithelial cells

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Figure 3. DBC1 is modified by SUMO1 rather than by SUMO2/3 in mouse lens. (A, B) The cell lysates of wildtype mouse lens epithelium were immunoprecipitated (IP) with anti-DBC1 (A) or anti-SUMO1 (B) antibody, followed by immunoblotting with anti-SUMO1 (A) or anti-DBC1 (B) antibody. (C, D) The cell lysates of wildtype mouse lens epithelium were immunoprecipitated (IP) with anti-DBC1 (C) or anti-SUMO2/3 (D) antibody, followed by immunoblotting with anti-SUMO2/3 (C) or anti-DBC1 (D) antibody.