Figure 5. Construction and validation of the prognostic signature. (A) The 10-fold cross-validation for the optimal parameter selection in the LASSO regression. (B) The profile of the LASSO coefficient. (C) The distribution plots of the risk score in the training set. (D) The survival status of BC patients in the training set. (E) The heatmap of 7 CRLs in the training set. (F) The distribution plots of the risk score in the testing set. (G) The survival status of BC patients in the testing set. (H) The heatmap of 7 CRLs in the testing set. (I) The distribution plots of the risk score in the entire set. (J) The survival status of BC patients in the entire set. (K) The heatmap of 7 CRLs in the entire set.