Research Paper Volume 15, Issue 14 pp 7258—7277
The lipid peroxidation-derived DNA adduct γ-OHPdG as a diagnostic and prognostic biomarker in hepatocellular carcinoma
Figure 1. The levels of γ-OHPdG by IHC staining in the development of HCC. (A) The levels of γ-OHPdG in the adjacent tissues, primary tumors, the recurrent and metastatic tumor tissues (20×); (B, C) Comparison of the levels of γ-OHPdG in HCC and the adjacent tissues; (D–G) The histogram plot shows γ-OHPdG levels in tumor size, Edmondson-Steiner grades I–IV, MVI grades 0-2, T stages T1a-T4 HCC patients, respectively; (H) Dot plot between γ-OHPdG levels and ki67 percentage scores; (I, J) γ-OHPdG levels between the recurrent tumors/metastatic tumors and their primary HCC tissues.*P < 0.05, **P < 0.01, ***P < 0.001 (Wilcoxon rank sum test and Kruskal-Wallis test).