Research Paper Volume 15, Issue 14 pp 7219—7236
Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma
Figure 7. Development and validation of the metastasis scoring system and distinct TME characteristics for OS. (A) Sankey Diagram of metastasis clusters, gene clusters, metastasis score, and clinical outcomes. Differences in metastasis score between (B) the three metastasis subtypes and (C) the two gene clusters. (D) Kaplan-Meier analysis of the OS between the two metastasis score groups. (E) Heatmap depicted the correlation between the metastasis score and different clinicopathological characteristics group. (F) Boxplots showed abundance of 23 infiltrating immune cell types. (G) Correlations between risk score and both immune and stromal scores. (H) Differences in metastasis scores between distinct survival status and the proportion of survival status of patients.