Priority Research Paper Volume 15, Issue 13 pp 5966—5989

Figure 1. The NCC reporter system to monitor cellular senescence. (A) The NCC reporter system integrated in human fibroblasts. (B) NCC signals in quiescent fibroblasts. (C) Fluorescence intensity profiles corresponding to the path of the arrow in (B). (D) The colocalization of mCherry and eGFP signals in quiescent fibroblasts by Pearson correlation. (E) NCC signals in senescent fibroblasts. (F) Fluorescence intensity profiles corresponding to the path of the arrow in (E). (G) The colocalization of mCherry and eGFP signals in senescent fibroblasts by Pearson correlation. (H) Pearson correlation of quiescent and senescent fibroblasts. Data are mean ± SD. ^****p < 0.0001. Two-tailed Student’s t test.