Research Paper Volume 15, Issue 14 pp 6950—6968

Single-cell sequencing analysis reveals the relationship between tumor microenvironment cells and oxidative stress in breast cancer bone metastases

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Figure 6. MSC subpopulations in patients with bone metastases from breast cancer. (A) Single-cell atlas showing MSC subpopulations. (B) Single-cell atlas showing MSC subpopulations in control and breast cancer bone metastasis patients. (C) Differential abundance of MSC subpopulations in control and breast cancer bone metastasis patients. (D) Marker genes specifically and highly expressed in subpopulations of MSC subpopulations. (E, F) Biological processes (E) and signaling pathways (F) enriched in MSC subpopulations. (G) Comparison of the differences in oxidative stress levels in MSC between control and bone metastasis samples.