Figure 4 — Single-cell sequencing analysis reveals the relationship between tumor microenvironment cells and oxidative stress in breast cancer bone metastases

Research Paper|Volume 15, Issue 14|pp. 6950–6968

Single-cell sequencing analysis reveals the relationship between tumor microenvironment cells and oxidative stress in breast cancer bone metastases

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Figure 4.Fibroblast subpopulations in patients with bone metastases from breast cancer. (A) Single-cell atlas showing fibroblast subpopulations. (B) Single-cell atlas showing fibroblast subpopulations in control and breast cancer bone metastasis patients. (C) Differences in abundance of fibroblast subpopulations in control and breast cancer bone metastasis patients. (D) Marker genes specifically and highly expressed in subpopulations of fibroblast subpopulations. (E, F). Biological processes (E) and signaling pathways (F) that enrich fibroblast subpopulations.