Research Paper Volume 15, Issue 14 pp 6950—6968

Single-cell sequencing analysis reveals the relationship between tumor microenvironment cells and oxidative stress in breast cancer bone metastases

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Figure 2. Breast cancer cell subpopulations in patients with bone metastases from breast cancer. (A) Single-cell atlas showing breast cancer cell subpopulations. (B) Single-cell atlas showing breast cancer cell subpopulations in control and breast cancer bone metastasis patients. (C) Differential abundance of breast cancer cell subpopulations in control and breast cancer bone metastasis patients. (D) Marker genes specifically and highly expressed in subpopulations of breast cancer cells. (E, F) Biological processes (E) and signaling pathways (F) enriched in breast cancer cell subpopulations. (G) Comparison of the differences in oxidative stress levels in breast cancer cells between control and bone metastasis samples.