Research Paper Volume 15, Issue 14 pp 6798—6821

Figure 5. Analysis of the immunomodulatory functions of C1 and C2 subtypes. (A) Differences in immunomodulator between subtypes C1 and C2 shown in a heatmap and orange represents high scores, and green represents low scores. (B) Differential expression of chemokines between C1 and C2 in TCGA cohort. (C) Differential expression of chemokine receptor between C1 and C2 in TCGA cohort. (D) Differential expression of immunostimulatory between C1 and C2 in TCGA cohort. (E) Differential expression of immunoinhibitor between C1 and C2 in TCGA cohort. (F) Differential expression of MHC between C1 and C2 in TCGA cohort. The line in the box represents the median value, and the asterisks represent the P-value (*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001). The statistical analyses were performed by the student t-test. TCGA, the cancer genome atlas; MHC, major histocompatibility complex.