Research Paper Volume 15, Issue 13 pp 6429—6444
Procoagulant genes may affect angiogenesis, epithelial-mesenchymal transition, survival prognosis and tumor immune microenvironment in patients with urothelial carcinoma
Figure 7. High coagulation-related risks were associated with poor PD1/PDL1 treatment outcomes and lower responses. (A) K-M curve analysis of coagulation-related risk signature in the GES176307 dataset. (B) four-grid table analysis of coagulation-related risk signature in the GES176307 dataset. The sensitivity of immunotherapy was higher in the low-risk group (31% vs. 13%). (C) box plot analysis of coagulation-related risk signature in the GES176307 dataset. The risk score was lower in the immunotherapy sensitive group. (D) K-M curve analysis of coagulation-related risk signature in the Imvigor210 dataset. (E) four-grid table analysis of coagulation-related risk signature in the Imvigor210 dataset. The sensitivity of immunotherapy was higher in the low-risk group (31% vs. 19%). (F) box plot analysis of coagulation-related risk signature in the Imvigor210 dataset. The risk score was lower in the immunotherapy sensitive group. (G, H) K-M curve, four-grid table analysis of TMB combined coagulation-related risk signature in the Imvigor210 dataset.