Research Paper Volume 15, Issue 13 pp 6429—6444
Procoagulant genes may affect angiogenesis, epithelial-mesenchymal transition, survival prognosis and tumor immune microenvironment in patients with urothelial carcinoma
Figure 4. The risk signature is closely related to tumor proliferation, metastasis, coagulation and angiogenesis. (A–G) Box plot of coagulation related risk score by age, gender, pathological grade, AJCC stage, TNM stage. A higher risk score means a higher T, N, AJCC-Stage and a higher grade. The difference was statistically significant. (H) GSEA pathways were enriched for angiogenesis based on coagulation-related risk score. NES = 1.995, p < 0.001. (I) Coagulation-related risk score was strongly positively correlated with angiogenesis. R = 0.32, p < 0.001. (J–M) The coagulation-related risk score was correlated with tumor proliferation, coagulation, and angiogenesis.