Research Paper Volume 15, Issue 13 pp 6429—6444

Figure 3. Validation of coagulation-related risk signature in TCGA set and external validation set. (A–C) PCA classification map, K-M curve, and ROC curve in TCGA dataset. The 1-year, 3-year, 5-year AUC of ROC curve is 0.75, 0.79, 0.75, respectively, while HR of KM curve is 3.43, p < 0.001. (D–F) PCA classification map, K-M curve, and ROC curve in external validation dataset. The 1-year, 3-year, 5-year AUC of ROC curve is 0.77, 0.64, 0.6, respectively, while HR of KM curve is 1.67, p = 0.031. (G) Multivariate COX regression forest map in TCGA dataset. Riskscore is an independent risk factor for prognosis. HR = 1.11, p < 0.001. (H) Multivariate COX regression forest map in external validation dataset. Riskscore is an independent risk factor for prognosis. HR = 1.08, p = 0.01.