Research Paper Volume 15, Issue 12 pp 5854—5872

Figure 6. Treatment with iPSC-derived exosomes and serum exosomes of young mice restored endothelial function. (A) iPSC-derived exosomes and serum exosomes of young mice promoted the proliferation of HUVEC. The proliferation of HUVEC was detected using CCK8 kit after H₂O₂ injury. (B) iPSC-derived exosomes and serum exosomes of young mice restored the ability of endothelial cells to form tube after H₂O₂ injury. Green fluorescence was observed to measure the tube formation by endothelial cells. HUVEC, human umbilical vein endothelial cell; LDL, low density lipoprotein; AC-LDL, acetylated low density lipoprotein.