Research Paper Volume 15, Issue 13 pp 6225—6254

Figure 7. Basic analysis of COL1A2. (A) Summary of the differential expression analysis of nine FARGs in three independent GBM cohorts and the GEPIA website. Red represents up-regulated genes in GBM tissue, while blue represents a down-regulated gene in GBM tissue. Grey represents no statistical difference. (B) Differential expression analysis of COL1A2 between GBM tissues and NBTs in TCGA (HG-UG133A), Kamoun and Rembrandt cohorts, and GEPIA website. (C) Immunohistochemical analysis of COL1A2 protein in eight pairs of GBM tissues and adjacent nontumor tissues. (D) The IHC scores of COL1A2 in GBM tissues and matched adjacent nontumor tissues. (E, F) The protein expression level of COL1A2 in GBM tissues was significantly higher than that in corresponding adjacent tissues. (G) K-M survival curves of OS in GBM patients between the high and low COL1A2 expression groups. *P < 0.05, **P < 0.01.