Research Paper Volume 15, Issue 12 pp 5673—5697

Figure 5. Contradistinction of genomic mutations between the two subgroups in the TCGA dataset. (A, B) Circos plots of low- and high-DUSP10 subgroups illustrated the amplifications and deletions of chromosomes, and boxplots exhibited a lower burden of copy number amplifications and deletions in the low-DUSP10 subgroup. (C, D) Waterfall plots revealed mutated genes in the low-DUSP10 (C) and high-DUSP10 (D) subgroups. (E, F) An association between DUSP10 expression and TMB levels. (G, H) Relationship between TMB level and the prognosis of patients with LGG (G) and the differential prognostic value in the two subtypes with distinct TMB level (H). ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.