Research Paper Volume 15, Issue 12 pp 5569—5591
Expression, prognostic value and mechanism of SP100 family in pancreatic adenocarcinoma
Figure 4. Gene enrichment analysis and PPI network construction of SP100 family in PAAD. (A) Top 50 genes co-expressed with SP100/SP110; (B) The Venn diagram of SP100 family members and their 400 co-expressed genes; (C) SP100 family members are also co-expressed among themselves. *p < 0.05; **p < 0.01; (D) The GO enrichment of the BP terms of the SP100 family and its 400 co-expressed genes; (E) The KEGG enrichment of the SP100 family and its 400 co-expressed genes; (F) SP100 family played an activating role in a variety of oncogenic pathways; (G, H) TP53 played an important role in PPI network which was closely related to SP100 family.